Abstraction can be helpful, but it also complicates things and leads to slower performance. Andrea Giammarchi provides lots of details here in examining a complex app scenario with the good old fashioned DOM vs. a handful of frameworks. Bonus points for the fact that most of the video evidence tests are being run on non-iOS devices!
No, the DOM is not your problem, the fact you brought an over-engineered abstraction on top of a deadly simple task, like a table that needs some quick update, is the real problem you don’t want to see.
If you dig Andrea’s post, you should also check out this post from the Filament Group.